基因组版本 Primary 和 Alternate的区别

Alternate
  • Primary assembly: a complete assembly with long stretches of phased blocks. The concept has been used by GRC. BAC-to-BAC assemblies can all be regarded as primary assemblies. Falcon-unzip is perhaps the first to produce such assemblies for whole-genome shotgun data.

  • Alternate assembly: an incomplete assembly consisting of haplotigs in heterozygous regions. An alternate assembly always accompanies a primary assembly. It is not useful by itself as it is fragmented and incomplete.



    https://lh3.github.io/2021/04/17/concepts-in-phased-assemblies

  • 发表于 2022-08-18 18:37
  • 阅读 ( 1683 )
  • 分类:基因组学

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